:root {
  --v500-ink: #101923;
  --v500-muted: #53606d;
  --v500-line: rgba(16, 25, 35, .13);
  --v500-paper: #f6f8f8;
  --v500-white: #ffffff;
  --v500-blue: #075ca8;
  --v500-blue-deep: #073e72;
  --v500-green: #087f58;
  --v500-green-soft: #dcefe8;
  --v500-radius: 14px;
  --v500-shadow: 0 24px 70px rgba(12, 32, 49, .10);
}

body.v500-site {
  background: var(--v500-paper);
  color: var(--v500-ink);
}

html body.v500-site.v500-site main h2::before {
  content: none !important;
  display: none !important;
  width: 0 !important;
  height: 0 !important;
  min-width: 0 !important;
  margin: 0 !important;
  animation: none !important;
}

html body.v500-site.v500-site main .v500-section--dark h2 {
  color: #eef5f7 !important;
}

html body.v500-site.v500-site main .v500-final h2 {
  color: #fff !important;
}

html body.v500-site.v500-site main > :is(
  .home-page-nav,
  .bioten-page-nav,
  .about-anchor-nav,
  .knowledge-anchor-nav,
  .resources-page-nav,
  .packaging-anchor,
  .news-business-anchor,
  .bioten-product-nav,
  .pl-anchor-nav,
  .vp-anchor-nav,
  .article-nav,
  .solutions-anchor
)::before {
  content: "内容导航" !important;
}

body.v500-site .site-header {
  background: rgba(250, 252, 252, .96);
}

.v500-shell {
  width: min(1440px, calc(100% - 96px));
  margin-inline: auto;
}

.v500-main {
  overflow: clip;
}

.v500-context {
  position: relative;
  z-index: 4;
  border-bottom: 1px solid var(--v500-line);
  background: rgba(255, 255, 255, .94);
}

.v500-context__inner {
  width: min(1440px, calc(100% - 96px));
  min-height: 48px;
  margin-inline: auto;
  display: flex;
  align-items: center;
  justify-content: space-between;
  gap: 32px;
}

.v500-context ol,
.v500-context__next {
  display: flex;
  align-items: center;
  gap: 10px;
  margin: 0;
  padding: 0;
  list-style: none;
  color: var(--v500-muted);
  font-size: 12px;
  letter-spacing: .02em;
}

.v500-context li:not(:last-child)::after {
  content: "/";
  margin-left: 10px;
  color: rgba(16, 25, 35, .35);
}

.v500-context a {
  color: inherit;
  text-decoration: none;
}

.v500-context a:hover,
.v500-context a:focus-visible {
  color: var(--v500-blue);
}

.v500-context__next {
  color: var(--v500-blue-deep);
  font-weight: 650;
}

.v500-context__next span:last-child {
  font-size: 16px;
}

.v500-hero {
  position: relative;
  min-height: 620px;
  padding: 76px 0 64px;
  display: grid;
  align-items: center;
  background:
    radial-gradient(circle at 78% 22%, rgba(8, 127, 88, .10), transparent 31%),
    linear-gradient(118deg, #f9fbfb 0%, #f2f7f8 58%, #eef6f4 100%);
  border-bottom: 1px solid var(--v500-line);
}

.v500-hero__grid {
  display: grid;
  grid-template-columns: minmax(0, .88fr) minmax(560px, 1.12fr);
  align-items: center;
  gap: clamp(52px, 6vw, 104px);
}

.v500-hero__copy {
  max-width: 650px;
}

.v500-kicker {
  margin: 0 0 18px;
  color: var(--v500-blue);
  font-size: 13px;
  font-weight: 720;
  letter-spacing: .1em;
}

.v500-kicker::before {
  content: "";
  display: inline-block;
  width: 24px;
  height: 2px;
  margin: 0 10px 4px 0;
  background: linear-gradient(90deg, var(--v500-blue), var(--v500-green));
}

.v500-hero h1 {
  max-width: none;
  margin: 0;
  font-size: clamp(48px, 4.4vw, 76px);
  line-height: 1.03;
  letter-spacing: -.055em;
  font-weight: 680;
  text-wrap: balance;
  word-break: auto-phrase;
}

.v500-hero__lead {
  max-width: 42em;
  margin: 26px 0 0;
  color: #3d4b58;
  font-size: 18px;
  line-height: 1.82;
}

.v500-actions {
  display: flex;
  flex-wrap: wrap;
  align-items: center;
  gap: 12px;
  margin-top: 34px;
}

.v500-button {
  min-height: 46px;
  padding: 0 20px;
  display: inline-flex;
  align-items: center;
  justify-content: center;
  gap: 18px;
  border: 1px solid var(--v500-line);
  border-radius: 10px;
  background: rgba(255, 255, 255, .82);
  color: var(--v500-ink);
  font-size: 14px;
  font-weight: 680;
  text-decoration: none;
  transition: transform .24s ease, border-color .24s ease, background .24s ease;
}

.v500-button:hover,
.v500-button:focus-visible {
  transform: translateY(-2px);
  border-color: rgba(7, 92, 168, .45);
  background: var(--v500-white);
}

.v500-button--primary {
  border-color: var(--v500-blue);
  background: var(--v500-blue);
  color: #fff;
}

.v500-button--primary:hover,
.v500-button--primary:focus-visible {
  border-color: var(--v500-blue-deep);
  background: var(--v500-blue-deep);
}

.v500-hero__visual {
  position: relative;
  min-height: 460px;
  margin: 0;
  overflow: hidden;
  border: 1px solid rgba(16, 25, 35, .11);
  border-radius: 18px;
  background: #e8eeee;
  box-shadow: var(--v500-shadow);
}

.v500-hero__visual::after {
  content: "";
  position: absolute;
  inset: 0;
  pointer-events: none;
  background: linear-gradient(135deg, rgba(255, 255, 255, .08), transparent 42%);
}

.v500-hero__visual img {
  width: 100%;
  height: 100%;
  min-height: 460px;
  display: block;
  object-fit: cover;
  object-position: var(--v500-image-position, 50% 50%);
}

.v500-hero__caption {
  position: absolute;
  z-index: 2;
  right: 22px;
  bottom: 18px;
  left: 22px;
  display: flex;
  justify-content: space-between;
  gap: 24px;
  color: #fff;
  font-size: 12px;
  letter-spacing: .03em;
}

.v500-facts {
  position: relative;
  z-index: 3;
  margin-top: -1px;
  border-bottom: 1px solid var(--v500-line);
  background: #fff;
}

.v500-facts__grid {
  min-height: 112px;
  display: grid;
  grid-template-columns: repeat(4, 1fr);
}

.v500-fact {
  padding: 24px 28px;
  display: grid;
  align-content: center;
  gap: 7px;
  border-left: 1px solid var(--v500-line);
}

.v500-fact:last-child {
  border-right: 1px solid var(--v500-line);
}

.v500-fact span {
  color: var(--v500-muted);
  font-size: 12px;
}

.v500-fact strong {
  font-size: 17px;
  line-height: 1.35;
  font-weight: 680;
}

.v500-section {
  padding: 82px 0;
  border-bottom: 1px solid var(--v500-line);
  background: #fff;
}

.v500-section--soft {
  background: #f0f4f4;
}

.v500-section--dark {
  color: #eef5f7;
  background: #0d202c;
}

.v500-section__head {
  max-width: 920px;
  display: block;
  margin-bottom: 38px;
}

.v500-section__head h2 {
  max-width: 22ch;
  margin: 0;
  font-size: clamp(34px, 2.8vw, 48px);
  line-height: 1.12;
  letter-spacing: -.045em;
  font-weight: 660;
  text-wrap: balance;
}

.v500-section__head p,
.v500-section__intro {
  max-width: 760px;
  margin: 16px 0 0;
  color: var(--v500-muted);
  font-size: 16px;
  line-height: 1.78;
}

.v500-section--dark .v500-section__head p,
.v500-section--dark .v500-section__intro {
  color: rgba(238, 245, 247, .68);
}

.v500-card-grid {
  display: grid;
  grid-template-columns: repeat(4, minmax(0, 1fr));
  gap: 16px;
}

.v500-card-grid--3 {
  grid-template-columns: repeat(3, minmax(0, 1fr));
}

.v500-card-grid--5 {
  grid-template-columns: repeat(5, minmax(0, 1fr));
}

.v500-card {
  min-height: 224px;
  padding: 28px;
  display: flex;
  flex-direction: column;
  border: 1px solid var(--v500-line);
  border-radius: var(--v500-radius);
  background: rgba(255, 255, 255, .92);
  box-shadow: 0 14px 36px rgba(13, 35, 50, .045);
}

.v500-card__number {
  color: var(--v500-blue);
  font-size: 12px;
  font-weight: 720;
  letter-spacing: .08em;
}

.v500-card h3 {
  margin: 0 0 14px;
  font-size: 23px;
  line-height: 1.25;
  letter-spacing: -.025em;
}

.v500-card p {
  margin: 0;
  color: var(--v500-muted);
  font-size: 14px;
  line-height: 1.78;
}

.v500-card a,
.v500-route a,
.v500-text-link {
  color: var(--v500-blue-deep);
  font-weight: 680;
  text-decoration: none;
}

.v500-card a {
  margin-top: auto;
  padding-top: 22px;
}

.v500-chain {
  display: grid;
  grid-template-columns: repeat(5, minmax(0, 1fr));
  border: 1px solid rgba(255, 255, 255, .14);
  border-radius: var(--v500-radius);
  overflow: hidden;
}

.v500-chain article {
  min-height: 228px;
  padding: 24px;
  border-right: 1px solid rgba(255, 255, 255, .14);
  background: rgba(255, 255, 255, .025);
}

.v500-chain article:last-child {
  border-right: 0;
}

.v500-chain span {
  color: #62d0ae;
  font-size: 12px;
}

.v500-chain strong {
  margin-top: 62px;
  display: block;
  font-size: 19px;
  line-height: 1.4;
}

.v500-chain p {
  margin: 10px 0 0;
  color: rgba(238, 245, 247, .66);
  font-size: 13px;
  line-height: 1.72;
}

.v500-route-grid {
  display: grid;
  grid-template-columns: repeat(3, minmax(0, 1fr));
  gap: 16px;
}

.v500-route-grid--4 {
  grid-template-columns: repeat(4, minmax(0, 1fr));
}

.v500-route-grid--4 .v500-route {
  min-height: 350px;
}

.v500-route {
  position: relative;
  min-height: 390px;
  overflow: hidden;
  border: 1px solid var(--v500-line);
  border-radius: var(--v500-radius);
  background: #dfe8e6;
}

.v500-route img {
  width: 100%;
  height: 100%;
  display: block;
  object-fit: cover;
  transition: transform .55s cubic-bezier(.2,.7,.2,1);
}

.v500-route:hover img {
  transform: scale(1.025);
}

.v500-route::after {
  content: "";
  position: absolute;
  inset: 18% 0 0;
  background: linear-gradient(180deg, transparent, rgba(5, 21, 31, .90));
}

.v500-route__copy {
  position: absolute;
  z-index: 2;
  right: 24px;
  bottom: 24px;
  left: 24px;
  color: #fff;
}

.v500-route__copy span {
  font-size: 12px;
  font-weight: 650;
  letter-spacing: .04em;
  opacity: .82;
}

.v500-route__copy h3 {
  margin: 8px 0;
  font-size: 24px;
  line-height: 1.25;
}

.v500-route__copy p {
  margin: 0 0 16px;
  color: rgba(255, 255, 255, .78);
  font-size: 13px;
  line-height: 1.68;
}

.v500-route__copy a {
  color: #fff;
}

.v500-evidence {
  display: grid;
  grid-template-columns: .72fr 1.28fr;
  gap: 64px;
  align-items: start;
}

.v500-evidence__intro h2 {
  margin: 0;
  font-size: 40px;
  line-height: 1.12;
  letter-spacing: -.04em;
}

.v500-evidence__intro p {
  margin: 20px 0 0;
  color: var(--v500-muted);
  line-height: 1.82;
}

.v500-evidence__list {
  display: grid;
  border-top: 1px solid var(--v500-line);
}

.v500-evidence__list article {
  padding: 20px 0;
  display: grid;
  grid-template-columns: 150px 1fr;
  gap: 24px;
  border-bottom: 1px solid var(--v500-line);
}

.v500-evidence__list strong {
  font-size: 14px;
}

.v500-evidence__list p {
  margin: 0;
  color: var(--v500-muted);
  font-size: 14px;
  line-height: 1.72;
}

.v500-final {
  padding: 72px 0;
  background: linear-gradient(112deg, var(--v500-blue-deep), #0a5f70 62%, var(--v500-green));
  color: #fff;
}

.v500-final__inner {
  display: grid;
  grid-template-columns: 1fr auto;
  align-items: center;
  gap: 56px;
}

.v500-final h2 {
  margin: 0;
  font-size: 38px;
  letter-spacing: -.035em;
}

.v500-final p {
  max-width: 760px;
  margin: 14px 0 0;
  color: rgba(255, 255, 255, .74);
  line-height: 1.75;
}

.v500-final .v500-button {
  border-color: rgba(255, 255, 255, .42);
  background: #fff;
  color: var(--v500-blue-deep);
}

.v500-site .formal-site-footer {
  border-top: 0;
}

.v500-site .footer-inner {
  width: min(1440px, calc(100% - 96px));
}

.v500-site .footer-directory {
  gap: 38px;
}

.v500-site .footer-column a {
  line-height: 1.55;
}

.v500-map-hero {
  padding: 72px 0 58px;
  border-bottom: 1px solid var(--v500-line);
  background:
    radial-gradient(circle at 84% 22%, rgba(8, 127, 88, .1), transparent 28%),
    linear-gradient(120deg, #fbfcfc, #eef5f5);
}

.v500-map-hero h1 {
  max-width: 18ch;
  margin: 0;
  font-size: 48px !important;
  line-height: 1.04;
  letter-spacing: -.045em;
}

.v500-map-hero p:last-child {
  max-width: 760px;
  margin: 20px 0 0;
  color: var(--v500-muted);
  font-size: 16px;
  line-height: 1.76;
}

.v500-map {
  padding: 64px 0 80px;
  background: #fff;
}

.v500-map-grid {
  display: grid;
  grid-template-columns: repeat(5, minmax(0, 1fr));
  border-top: 1px solid var(--v500-line);
  border-bottom: 1px solid var(--v500-line);
}

.v500-map__group {
  min-height: 520px;
  padding: 28px 24px;
  border-left: 1px solid var(--v500-line);
}

.v500-map__group:last-child {
  border-right: 1px solid var(--v500-line);
}

.v500-map__group > span {
  color: var(--v500-blue);
  font-size: 12px;
  font-weight: 760;
  letter-spacing: .08em;
}

.v500-map__group h2 {
  margin: 28px 0 10px;
  font-size: 25px !important;
  letter-spacing: -.025em;
}

.v500-map__group > p {
  min-height: 76px;
  margin: 0 0 26px;
  color: var(--v500-muted);
  font-size: 13px;
  line-height: 1.62;
}

.v500-map__group ul {
  margin: 0;
  padding: 0;
  list-style: none;
  border-top: 1px solid var(--v500-line);
}

.v500-map__group li {
  border-bottom: 1px solid var(--v500-line);
}

.v500-map__group a {
  padding: 12px 0;
  display: flex;
  align-items: center;
  justify-content: space-between;
  gap: 12px;
  color: var(--v500-ink);
  font-size: 13px;
  font-weight: 650;
  line-height: 1.35;
  text-decoration: none;
}

.v500-map__group a::after {
  content: "→";
  flex: 0 0 auto;
  color: var(--v500-blue);
}

.v500-map__group a:hover,
.v500-map__group a:focus-visible {
  color: var(--v500-blue);
}

@media (min-width: 1024px) and (max-width: 1280px) {
  .v500-shell,
  .v500-context__inner,
  .v500-site .footer-inner {
    width: min(1180px, calc(100% - 56px));
  }

  .v500-hero {
    min-height: 560px;
    padding-block: 56px;
  }

  .v500-hero__grid {
    grid-template-columns: .9fr 1.1fr;
    gap: 46px;
  }

  .v500-hero h1 {
    font-size: 48px;
  }

  .v500-hero__visual,
  .v500-hero__visual img {
    min-height: 400px;
  }

  .v500-section {
    padding-block: 70px;
  }

  .v500-card {
    min-height: 218px;
    padding: 22px;
  }

  .v500-chain article {
    padding: 20px;
  }

  html body.v245-page.v282-site.v500-site #main-content #health-title {
    font-size: 48px !important;
    line-height: 1.06 !important;
    letter-spacing: -0.045em !important;
  }
}

@media (max-width: 1023px) {
  .v500-shell,
  .v500-context__inner,
  .v500-site .footer-inner {
    width: min(100% - 36px, 760px);
  }

  .v500-context__next { display: none; }
  .v500-hero__grid,
  .v500-section__head,
  .v500-evidence,
  .v500-final__inner { grid-template-columns: 1fr; }
  .v500-hero__grid { gap: 36px; }
  .v500-hero h1 { font-size: 46px; }
  .v500-facts__grid,
  .v500-card-grid { grid-template-columns: repeat(2, 1fr); }
  .v500-chain { grid-template-columns: 1fr; }
  .v500-chain article { min-height: auto; border-right: 0; border-bottom: 1px solid rgba(255,255,255,.14); }
  .v500-chain strong { margin-top: 22px; }
  .v500-route-grid { grid-template-columns: 1fr; }
}

@media (prefers-reduced-motion: reduce) {
  .v500-button,
  .v500-route img { transition: none; }
}